Article
A "traffic control" role for TGFbeta3: orchestrating dermal and epidermal cell motility during wound healing.
The Journal of cell biology - 27 Mar 2006
Bandyopadhyay Balaji, Fan Jianhua, Guan Shengxi, Li Yong, Chen Mei, Woodley David T, Li Wei
Abstract excerpt
Cell migration is a rate-limiting event in skin wound healing. In unwounded skin, cells are nourished by plasma. When skin is wounded, resident cells encounter serum for the first time. As the wound heals, the cells experience a transition of serum back to plasma. In this study, we report that human serum selectively promotes epidermal cell migration and halts dermal cell migration. In contrast, human plasma...
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