Article
Transforming growth factor alpha (TGFalpha)-stimulated secretion of HSP90alpha: using the receptor LRP-1/CD91 to promote human skin cell migration against a TGFbeta-rich environment during wound healing.
Molecular and cellular biology - 1 May 2008
Cheng Chieh-Fang, Fan Jianhua, Fedesco Mark, Guan Shengxi, Li Yong, Bandyopadhyay Balaji, Bright Alexandra M, Yerushalmi Dalia, Liang Mengmeng, Chen Mei, Han Yuan-Ping, Woodley David T, Li Wei
Abstract excerpt
Jump-starting and subsequently maintaining epidermal and dermal cell migration are essential processes for skin wound healing. These events are often disrupted in nonhealing wounds, causing patient morbidity and even fatality. Currently available treatments are unsatisfactory. To identify novel wound-healing targets, we investigated secreted molecules from transforming growth factor alpha (TGFalpha)-stimulated...
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