Article
Bone morphogenetic proteins: an unconventional approach to isolation of first mammalian morphogens.
Cytokine & growth factor reviews - 1 Mar 1997
Reddi A H
Abstract excerpt
It is conventional to identify morphogens from fly and frog embryos during morphogenesis using gene-screens, subtractive hybridizations, differential displays and expression cloning. This information is then extended to mice and men. The bone morphogenetic proteins (BMPs) are a family of pleiotropic morphogens/cytokines isolated and cloned from the demineralized extracellular matrix of adult bone. Thus, BMPs were...
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