Article
Dynamic control of yeast MAP kinase network by induced association and dissociation between the Ste50 scaffold and the Opy2 membrane anchor.
Molecular cell - 8 Oct 2010
Yamamoto Katsuyoshi, Tatebayashi Kazuo, Tanaka Keiichiro, Saito Haruo
Abstract excerpt
Membrane localization of the Ste11 MAPKKK is essential for activation of both the filamentous growth/invasive growth (FG/IG) MAP kinase (MAPK) pathway and the SHO1 branch of the osmoregulatory HOG MAPK pathway, and is mediated by binding of the Ste50 scaffold protein to the Opy2 membrane anchor....
Topics
- Amino Acid Sequence
- Binding Sites
- Casein Kinase I
- Cytoplasm
- Feedback, Physiological
- Glucose
- MAP Kinase Signaling System
- Membrane Proteins
- Mitogen-Activated Protein Kinases
- Molecular Sequence Data
- Mutation
- Phosphoprotein Phosphatases
- Phosphorylation
- Protein Binding
- Protein Interaction Domains and Motifs
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Time Factors