Article
Control of MAPK specificity by feedback phosphorylation of shared adaptor protein Ste50.
The Journal of biological chemistry - 5 Dec 2008
Hao Nan, Zeng Yaxue, Elston Timothy C, Dohlman Henrik G
Abstract excerpt
Many different signaling pathways share common components but nevertheless invoke distinct physiological responses. In yeast, the adaptor protein Ste50 functions in multiple mitogen-activated protein (MAP) kinase pathways, each with unique dynamical and developmental properties. Although Kss1 act...
Topics
- Binding Sites
- Feedback, Physiological
- Gene Expression Regulation, Enzymologic
- Gene Expression Regulation, Fungal
- MAP Kinase Signaling System
- Mitogen-Activated Protein Kinases
- Mutation
- Osmosis
- Phosphorylation
- Promoter Regions, Genetic
- Protein Structure, Tertiary
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Time Factors