Article
Signaling in the yeast pheromone response pathway: specific and high-affinity interaction of the mitogen-activated protein (MAP) kinases Kss1 and Fus3 with the upstream MAP kinase kinase Ste7.
Molecular and cellular biology - 1 Jul 1996
Bardwell L, Cook J G, Chang E C, Cairns B R, Thorner J
Abstract excerpt
Kss1 and Fus3 are mitogen-activated protein kinases (MAPKs or ERKs), and Ste7 is their activating MAPK/ERK kinase (MEK), in the pheromone response pathway of Saccharomyces cerevisiae. To investigate the potential role of specific interactions between these enzymes during signaling, their ability...
Topics
- Base Sequence
- Binding Sites
- Calcium-Calmodulin-Dependent Protein Kinases
- Cloning, Molecular
- Escherichia coli
- Fungal Proteins
- Mitogen-Activated Protein Kinase Kinases
- Mitogen-Activated Protein Kinases
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Oligodeoxyribonucleotides
- Phenotype