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Article

The MAPKKK Ste11 regulates vegetative growth through a kinase cascade of shared signaling components.

Proceedings of the National Academy of Sciences of the United States of America - 26 Oct 1999

Lee B N, Elion E A

Abstract excerpt

In haploid Saccharomyces cerevisiae, the mating and invasive growth (IG) pathways use the same mitogen-activated protein kinase kinase kinase kinase (MAPKKKK, Ste20), MAPKKK (Ste11), MAPKK (Ste7), and transcription factor (Ste12) to promote either G(1) arrest and fusion or foraging in response to distinct stimuli. This exquisite specificity is the result of pathway-specific receptors, G proteins, scaffold...

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Identifiers

PMID: 10535982
DOI: 10.1073/pnas.96.22.12679
PMCID: PMC23046

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The MAPKKK Ste11 regulates vegetative growth through a kinase cascade of shared signaling components.PMID 10535982Read ↗

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Elements of a single MAP kinase cascade in Saccharomyces cerevisiae mediate two developmental programs in the same cell type: mating and invasive growth.Semantic proximity Read ↗

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