Article
The MAPKKK Ste11 regulates vegetative growth through a kinase cascade of shared signaling components.
Proceedings of the National Academy of Sciences of the United States of America - 26 Oct 1999
Lee B N, Elion E A
Abstract excerpt
In haploid Saccharomyces cerevisiae, the mating and invasive growth (IG) pathways use the same mitogen-activated protein kinase kinase kinase kinase (MAPKKKK, Ste20), MAPKKK (Ste11), MAPKK (Ste7), and transcription factor (Ste12) to promote either G(1) arrest and fusion or foraging in response to distinct stimuli. This exquisite specificity is the result of pathway-specific receptors, G proteins, scaffold...
Topics
- Calcium-Calmodulin-Dependent Protein Kinases
- Cell Division
- Cell Wall
- Cloning, Molecular
- Gene Expression Regulation, Enzymologic
- Gene Expression Regulation, Fungal
- Glucosyltransferases
- MAP Kinase Kinase Kinases
- MAP Kinase Signaling System
- Membrane Proteins
- Mitogen-Activated Protein Kinases
- Mutation