p53 regulation of DNA excision repair pathways.

doi:10.1093/mutage/17.2.149

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Article

p53 regulation of DNA excision repair pathways.

Mutagenesis - 1 Mar 2002

Smith Martin L, Seo Young R

Abstract excerpt

The regulation of DNA excision repair pathways by p53 and its downstream genes is an emerging body of literature, largely distinct and separable from the more-studied cell cycle arrest and apoptosis responses regulated by p53. Regulation of nucleotide excision repair of UV-damage by p53 and its downstream genes Gadd45 and p48XPE has been well-documented, but much remains to be done in elucidating mechanisms....

Topics

Animals
Apoptosis
Cell Cycle
DNA Damage
DNA Repair
Humans
Mutation
Neoplasms
Nuclear Proteins
Signal Transduction
Tumor Suppressor Protein p53

Source

Open in PubMed

Identifiers

PMID: 11880544
DOI: 10.1093/mutage/17.2.149

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