Article
Interplay between p53-family, their regulators, and PARPs in DNA repair.
Clinics and research in hepatology and gastroenterology - 1 Feb 2011
Emami S
Abstract excerpt
Abnormalities of the p53 tumor suppressor gene are among the most frequent molecular events in human neoplasia. p53 is consequently one of the most studied proteins, and is the subject of over 55,500 scientific papers. In this review, attention is focused on the functions of p53 in DNA repair. We highlight the recent progress in the analysis of protein signals to p53, including PARPs, and ubiquitination cascade...
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