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Article

Significant effect of homologous recombination DNA repair gene polymorphisms on pancreatic cancer survival.

Cancer research - 15 Mar 2006

Li Donghui, Liu Hui, Jiao Li, Chang David Z, Beinart Garth, Wolff Robert A, Evans Douglas B, Hassan Manal M, Abbruzzese James L

Abstract excerpt

Genetic variation in DNA repair may affect the clinical response to cytotoxic therapies. We investigated the effect of six single nucleotide polymorphisms of the RecQ1, RAD54L, XRCC2, and XRCC3 genes on overall survival of 378 patients with pancreatic adenocarcinoma who were treated at University of Texas M.D. Anderson Cancer Center during February 1999 to October 2004 and were followed up to October 2005....

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Share to Adenosine Triphosphatases
Share to Carcinoma, Pancreatic Ductal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 16540687
DOI: 10.1158/0008-5472.CAN-05-3032
PMCID: PMC1462866

Genes

XRCC2
XRCC3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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