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Article

Single nucleotide polymorphisms of RecQ1, RAD54L, and ATM genes are associated with reduced survival of pancreatic cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Apr 2006

Li Donghui, Frazier Marsha, Evans Douglas B, Hess Kenneth R, Crane Christopher H, Jiao Li, Abbruzzese James L

Abstract excerpt

PURPOSE: Our goal was to determine whether single nucleotide polymorphisms (SNPs) in DNA repair genes influence the clinical outcome of pancreatic cancer. PATIENTS AND METHODS: We evaluated 13 SNPs of eight DNA damage response and repair genes in 92 patients with potentially resectable pancreatic adenocarcinoma. All patients were treated with neoadjuvant concurrent gemcitabine and radiotherapy with or without a...

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Source

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Identifiers

PMID: 16520463
DOI: 10.1200/JCO.2005.04.4206
PMCID: PMC1435378

Genes

ATM
XRCC1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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