Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

H-RAS 81 polymorphism is significantly associated with aneuploidy in follicular tumors of the thyroid.

Oncogene - 3 Aug 2006

Castro P, Soares P, Gusmão L, Seruca R, Sobrinho-Simões M

Abstract excerpt

Follicular thyroid tumors are often aneuploid. It was advanced that chromosomal instability is closely associated to RAS mutations, but such association remains unproven. H-RAS can be alternatively spliced in two different proteins, p21 and p19, the former being the active protein. In order to investigate the relationship between RAS mutational status and ploidy in thyroid tumors, we analysed RAS genes in a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma, Follicular
Share to Alternative Splicing
Share to Aneuploidy

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Neoplasm

Share to Genes, ras

Share to Ploidies

Share to ras Proteins

Share to Thyroid Neoplasms

Source

Identifiers

PMID: 16532025
DOI: 10.1038/sj.onc.1209491

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

H-RAS 81 polymorphism is significantly associated with aneuploidy in follicular tumors of the thyroid.PMID 16532025Read ↗

Specific pattern of RAS oncogene mutations in follicular thyroid tumors.Semantic proximity Read ↗

<i>RAS</i>Point Mutations and PAX8-PPARγ Rearrangement in Thyroid Tumors: Evidence for Distinct Molecular Pathways in Thyroid Follicular CarcinomaSemantic proximity Read ↗

Ras oncogene mutations in benign and malignant thyroid neoplasms.Semantic proximity Read ↗

Prevalence of activating ras mutations in morphologically characterized thyroid nodules.Semantic proximity Read ↗

The RAS oncogene induces genomic instability in thyroid PCCL3 cells via the MAPK pathway.Semantic proximity Read ↗

Prevalence of Ras mutations in thyroid neoplasia.Semantic proximity Read ↗

H-ras protooncogene mutations in human thyroid neoplasms.Semantic proximity Read ↗

Lack of mutational events of RAS genes in sporadic thyroid cancer but high risk associated with HRAS T81C single nucleotide polymorphism (case-control study).Semantic proximity Read ↗

Evaluation of somatic genomic imbalances in thyroid carcinomas of follicular origin by CGH-based approaches.Semantic proximity Read ↗

Comparative genomic hybridization, BRAF, RAS, RET, and oligo-array analysis in aneuploid papillary thyroid carcinomasSemantic proximity Read ↗

RAS mutations in thyroid cancer.Semantic proximity Read ↗

N-ras mutation of thyroid tumor with special reference to the follicular type.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.