Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lack of mutational events of RAS genes in sporadic thyroid cancer but high risk associated with HRAS T81C single nucleotide polymorphism (case-control study).

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Feb 2013

Khan Mosin S, Pandith Arshad A, Ul Hussain Mahboob, Iqbal Mohammad, Khan Nighat P, Wani Khurshid A, Masoodi Shariq R, Mudassar Syed

Abstract excerpt

High incidence of thyroid cancer worldwide indicates the importance of studying genetic alterations that lead to its carcinogenesis. Specific acquired RAS mutations have been found to predominate in different cancers, and HRAS T81C polymorphism has been determined to contribute the risk of various cancers, including thyroid cancer. We screened the exons 1 and 2 of RAS genes (HRAS, KRAS, and NRAS) in 60...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma, Follicular
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genes, ras

Share to Polymorphism, Restriction Fragment Length

Share to Proto-Oncogene Proteins p21(ras)

Share to Smoking

Share to Thyroid Neoplasms

Source

Identifiers

PMID: 23150177
DOI: 10.1007/s13277-012-0577-y

Genes

HRAS
KRAS
NRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lack of mutational events of RAS genes in sporadic thyroid cancer but high risk associated with HRAS T81C single nucleotide polymorphism (case-control study).PMID 23150177Read ↗

Clinical utility of RAS mutations in thyroid cancer: a blurred picture now emerging clearerSemantic proximity Read ↗

Novel RET Proto-oncogene variants identified in Turkish patients with thyroid carcinoma.Semantic proximity Read ↗

Polymorphisms of DNA Repair Genes in Thyroid Cancer.Semantic proximity Read ↗

Association analysis between the interaction of RAS family genes mutations and papillary thyroid carcinoma in the Han Chinese population.Semantic proximity Read ↗

[Mutation of RAS gene in follicular-differentiated thyroid tumors and its significance].Semantic proximity Read ↗

Identification of RASAL1 as a major tumor suppressor gene in thyroid cancer.Semantic proximity Read ↗

The associations between RAS mutations and clinical characteristics in follicular thyroid tumors: new insights from a single center and a large patient cohort.Semantic proximity Read ↗

RAS proto-oncogene in medullary thyroid carcinoma.Semantic proximity Read ↗

Comprehensive survey of HRAS, KRAS, and NRAS mutations in proliferative thyroid lesions from an ethnically diverse population.Semantic proximity Read ↗

[Advances in studies of the genes related to thyroid carcinoma].Semantic proximity Read ↗

Analysis of somatic mutations in BRAF, CDKN2A/p16 and PI3KCA in patients with medullary thyroid carcinoma.Semantic proximity Read ↗

Significance of the RET proto-oncogene polymorphisms in Turkish sporadic medullary thyroid carcinoma patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.