Article
Histopathology of BRCA1- and BRCA2-associated breast cancer.
Critical reviews in oncology/hematology - 1 Jul 2006
Honrado Emiliano, Benítez Javier, Palacios José
Abstract excerpt
Hereditary breast carcinomas that are attributable to BRCA1/2 mutations have their own morphological and immunohistochemical characteristics. BRCA1-associated carcinomas are poorly differentiated infiltrating ductal carcinomas that frequently show morphological features of typical or atypical medullary carcinoma. BRCA2-associated breast carcinomas tend to be of higher grade than sporadic age-matched controls....
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