Article
Clinico-pathological characteristics of BRCA1- and BRCA2-related breast cancer.
Seminars in surgical oncology - 1 Jun 2000
Chappuis P O, Nethercot V, Foulkes W D
Abstract excerpt
Approximately 2% to 5% of all breast cancers are hereditary, meaning that the cancer predisposition is carried as a monogenic trait. Several highly penetrant breast cancer predisposing genes have been identified. These discoveries will permit a refined description of breast cancer occurring as part of the different genetic syndromes. We reviewed the medical literature on the clinico-pathological features of...
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