Article
BRCA2 mutation-associated breast cancers exhibit a distinguishing phenotype based on morphology and molecular profiles from tissue microarrays.
The American journal of surgical pathology - 1 Jan 2007
Bane Anita L, Beck Jeanne C, Bleiweiss Ira, Buys Saundra S, Catalano Edison, Daly Mary B, Giles Graham, Godwin Andy K, Hibshoosh Hanina, Hopper John L, John Esther M, Layfield Lester, Longacre Teri, Miron Alexander, Senie Rubie, Southey Melissa C, West Dee W, Whittemore Alice S, Wu Hong, Andrulis Irene L, O'Malley Frances P
Abstract excerpt
A distinct morphologic and molecular phenotype has been reported for BRCA1-associated breast cancers; however, the phenotype of BRCA2-associated breast cancers is less certain. To comprehensively characterize BRCA2-associated breast cancers we performed a retrospective case control study using tu...
Topics
- Adult
- Aged
- BRCA2 Protein
- Biomarkers, Tumor
- Breast Neoplasms
- Carcinoma, Ductal, Breast
- Case-Control Studies
- DNA Mutational Analysis
- Female
- Humans