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Article

Associations of apolipoprotein E gene with ischemic stroke and intracranial atherosclerosis.

European journal of human genetics : EJHG - 1 Aug 2008

Abboud Shérine, Viiri Leena E, Lütjohann Dieter, Goebeler Sirkka, Luoto Teemu, Friedrichs Silvia, Desfontaines Philippe, Gazagnes Marie-dominique, Laloux Patrice, Peeters André, Seeldrayers Pierrette, Lehtimaki Terho, Karhunen Pekka, Pandolfo Massimo, Laaksonen Reijo

Abstract excerpt

The apolipoprotein E (APOE) epsilon4 allele is associated with elevated cholesterol and risk of atherosclerosis. However, its role in ischemic stroke (IS) remains controversial. We investigated a possible link between IS or the severity of intracranial atherosclerosis and the APOE promoter polymo...

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Source

Identifiers

PMID: 18301447
DOI: 10.1038/ejhg.2008.27

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18301447-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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