Article
Apolipoprotein E polymorphisms predict low density lipoprotein cholesterol levels and carotid artery wall thickness but not incident coronary heart disease in 12,491 ARIC study participants.
American journal of epidemiology - 15 Aug 2006
Volcik Kelly A, Barkley Ruth Ann, Hutchinson Richard G, Mosley Thomas H, Heiss Gerardo, Sharrett A Richey, Ballantyne Christie M, Boerwinkle Eric
Abstract excerpt
Elevated levels of low density lipoprotein (LDL) cholesterol is a well-established risk factor for cardiovascular disease, and recent advancements have provided evidence that carotid artery intima-media thickness (IMT) is associated with increased occurrence of cardiovascular events. Apolipoprotein E (ApoE) has been widely studied in regard to its role in lipid transport and metabolism, but the role that ApoE...
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