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Article

Interactions of functional apolipoprotein E gene promoter polymorphisms with smoking on aortic atherosclerosis.

Circulation. Cardiovascular genetics - 1 Dec 2008

Viiri Leena E, Viiri Keijo M, Ilveskoski Erkki, Huhtala Heini, Mäki Markku, Tienari Pentti J, Perola Markus, Lehtimäki Terho, Karhunen Pekka J

Abstract excerpt

BACKGROUND: Apolipoprotein E gene (APOE) interacts with environmental factors in defining risk for atherosclerosis. We studied whether the APOE epsilon2/epsilon3/epsilon4 genotype or APOE promoter polymorphisms -219G/T and +113G/C might interact with smoking on the development of fatty streaks. W...

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Source

Identifiers

PMID: 20031552
DOI: 10.1161/CIRCGENETICS.108.791764

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20031552-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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