Article
Apolipoprotein E phenotypes in Finnish youths: a cross-sectional and 6-year follow-up study.
Journal of lipid research - 1 Mar 1990
Lehtimäki T, Moilanen T, Viikari J, Akerblom H K, Ehnholm C, Rönnemaa T, Marniemi J, Dahlen G, Nikkari T
Abstract excerpt
Apolipoprotein E (apoE) polymorphism is a genetic determinant of plasma lipid levels and of coronary heart disease (CHD) risk. We determined the apoE phenotypes and plasma lipid levels in 1577 youths aged 3 to 18 years in 1980. The subjects were randomly selected from five areas of Finland. ApoE phenotyping was performed directly from plasma by isoelectric focusing and immunoblotting. The apoE allele frequencies...
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