Article
Genetic and antigenic diversity among noroviruses.
The Journal of general virology - 1 Apr 2006
Hansman Grant S, Natori Katsuro, Shirato-Horikoshi Haruko, Ogawa Satoko, Oka Tomoichiro, Katayama Kazuhiko, Tanaka Tomoyuki, Miyoshi Tatsuya, Sakae Kenji, Kobayashi Shinichi, Shinohara Michiyo, Uchida Kazue, Sakurai Nakao, Shinozaki Kuniko, Okada Mineyuki, Seto Yoshiyuki, Kamata Kunio, Nagata Noriyo, Tanaka Keiko, Miyamura Tatsuo, Takeda Naokazu
Abstract excerpt
Human norovirus (NoV) strains cause a considerable number of outbreaks of gastroenteritis worldwide. Based on their capsid gene (VP1) sequence, human NoV strains can be grouped into two genogroups (GI and GII) and at least 14 GI and 17 GII genotypes (GI/1-14 and GII/1-17). Human NoV strains cannot be propagated in cell-culture systems, but expression of recombinant VP1 in insect cells results in the formation of...
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