Article
Biological and immunological characterization of major capsid protein VP1 from distinct GII.2 norovirus clusters.
Scientific reports - 9 Sept 2024
Ma Jie, Liu Jinjin, Huo Yuqi
Abstract excerpt
Human noroviruses (HuNoVs) are a leading cause of acute viral gastroenteritis worldwide. Infectious outbreaks due to recombinant NoV genotype called GII.P16-GII.2 have been frequently reported since 2016. In this study, we expressed the major capsid protein VP1 from three GII.2 NoV strains using the recombinant baculovirus expression system. The assembly, histo-blood group antigen (HBGA)-binding patterns, and...
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