Article
Characterization of a cross-reactive monoclonal antibody against Norovirus genogroups I, II, III and V.
Virus research - 1 Aug 2010
Li Xiao, Zhou Rong, Tian Xingui, Li Haitao, Zhou Zhichao
Abstract excerpt
Noroviruses cause the majority of epidemic outbreaks of acute viral gastroenteritis worldwide. In a previous study of monoclonal antibodies against Norovirus GII/4 strain, we identified a continuous epitope (55)WIRNNF(60) that was recognized by MAb N2C3. Subsequent studies found that this MAb could recognize several different strains of Noroviruses, not just GII/4. In the present study, we used homology modeling...
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