Article
Anti-norovirus polyclonal antibody and its potential for development of an antigen-ELISA.
Journal of medical virology - 1 Aug 2007
Okame Michio, Shiota Tomoyuki, Hansman Grant, Takagi Makiko, Yagyu Fumihiro, Takanashi Sayaka, Phan Tung Gia, Shimizu Yuko, Kohno Hideki, Okitsu Shoko, Ushijima Hiroshi
Abstract excerpt
Norovirus (NoV) capsid proteins were expressed as virus-like particles (VLPs) by using recombinant baculovirus in insect cells, which had 5 genotypes in genogroup I and 11 genotypes in genogroup II, and the VLPs were used as immunogens. Polyclonal antibody against the VLP of GII/3 genotype showed broad-range cross-reactivity, reacting not only with intra-genogroup strains, but also inter-genogroup strains, by...
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