Article
Serotonin transporter gene promoter polymorphism predicts SSRI response in generalized social anxiety disorder.
Psychopharmacology - 1 Jul 2006
Stein Murray B, Seedat Soraya, Gelernter Joel
Abstract excerpt
OBJECTIVES: To determine whether variation in the serotonin transporter gene promoter (5HTTLPR) influences the efficacy of selective serotonin reuptake inhibitors (SSRIs) in generalized social anxiety disorder (GSAD). METHODS: Consecutive series of N=32 patients with DSM-IV GSAD for whom DNA and standardized outcome data from a 12-week SSRI trial were available. After ensuring that neither clinical response...
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