Article
Association between serotonin transporter gene promoter-region polymorphism and 4- and 12-week treatment response to sertraline in posttraumatic stress disorder.
Journal of affective disorders - 1 Feb 2012
Mushtaq Dhuha, Ali Arif, Margoob Mushtaq A, Murtaza Imtiyaz, Andrade Chittaranjan
Abstract excerpt
BACKGROUND: We examined the association between serotonin transporter (5HTTLPR) genotype (SS vs SL vs LL) and sertraline treatment outcome in posttraumatic stress disorder (PTSD). METHODS: Outpatients (n=330) with PTSD underwent 5HTTLPR genotyping. All patients received sertraline (100 mg/day) for 12 weeks. Patients were assessed using the Clinician-Administered PTSD Scale (CAPS) and other instruments. Patients...
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