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Article

Role of the serotonin transporter gene locus in the response to SSRI treatment of major depressive disorder in late life.

Journal of psychopharmacology (Oxford, England) - 1 May 2015

Seripa Davide, Pilotto Andrea, Paroni Giulia, Fontana Andrea, D'Onofrio Grazia, Gravina Carolina, Urbano Maria, Cascavilla Leandro, Paris Francesco, Panza Francesco, Padovani Alessandro, Pilotto Alberto

Abstract excerpt

It has been suggested that the serotonin or 5-hydroxytriptamine (5-HT) transporter (5-HTT) and its gene-linked polymorphic region (5-HTTLPR) are selective serotonin reuptake inhibitor (SSRI) response modulators in late-life depression (LLD), and particularly in late-life major depressive disorder (MDD). Previous studies differed in design and results. Our study aimed to investigate the solute carrier family 6...

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PMID: 25827644
DOI: 10.1177/0269881115578159

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HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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