Article
Arl2 and Arl3 regulate different microtubule-dependent processes.
Molecular biology of the cell - 1 May 2006
Zhou Chengjing, Cunningham Leslie, Marcus Adam I, Li Yawei, Kahn Richard A
Abstract excerpt
Arl2 and Arl3 are closely related members of the Arf family of regulatory GTPases that arose from a common ancestor early in eukaryotic evolution yet retain extensive structural, biochemical, and functional features. The presence of Arl3 in centrosomes, mitotic spindles, midzones, midbodies, and cilia are all supportive of roles in microtubule-dependent processes. Knockdown of Arl3 by siRNA resulted in changes in...
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