Article
ADP-ribosylation factor-like 3 is involved in kidney and photoreceptor development.
The American journal of pathology - 1 Apr 2006
Schrick Jeffrey J, Vogel Peter, Abuin Alejandro, Hampton Billy, Rice Dennis S
Abstract excerpt
ADP-ribosylation factor-like 3 (Arl3) is a member of a small subfamily of G-proteins involved in membrane-associated vesicular and intracellular trafficking processes. Genetic studies in Leishmania have shown that the Arl3 homolog is essential for flagellum biogenesis. Mutations in a related human family member, Arl6, result in Bardet-Biedl syndrome in humans, which is characterized by genital, renal, and retinal...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
