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Article

The small GTPase ARL2 is required for cytokinesis in Trypanosoma brucei

2 Jun 2010

Abstract excerpt

The Arf-like (Arl) small GTPases have a diverse range of functions in the eukaryotic cell. Metazoan Arl2 acts as a regulator of microtubule biogenesis, binding to the tubulin-specific chaperone cofactor D. Arl2 also has a mitochondrial function through its interactions with BART and ANT-1, the only member of the Ras superfamily to be found in this organelle to date. In the present study, we describe...

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PMID: 20653091
DOI: 10.1016/j.molbiopara.2010.05.016

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