Article
ARL4D recruits cytohesin-2/ARNO to modulate actin remodeling.
Molecular biology of the cell - 1 Nov 2007
Li Chun-Chun, Chiang Tsai-Chen, Wu Tsung-Sheng, Pacheco-Rodriguez Gustavo, Moss Joel, Lee Fang-Jen S
Abstract excerpt
ARL4D is a developmentally regulated member of the ADP-ribosylation factor/ARF-like protein (ARF/ARL) family of Ras-related GTPases. Although the primary structure of ARL4D is very similar to that of other ARF/ARL molecules, its function remains unclear. Cytohesin-2/ARF nucleotide-binding-site opener (ARNO) is a guanine nucleotide-exchange factor (GEF) for ARF, and, at the plasma membrane, it can activate ARF6 to...
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