Article
G-Protein-coupled receptor polymorphisms are associated with asthma in a large German population.
American journal of respiratory and critical care medicine - 15 Jun 2005
Kormann Michael S D, Carr David, Klopp Norman, Illig Thomas, Leupold Wolfgang, Fritzsch Christian, Weiland Stephan K, von Mutius Erika, Kabesch Michael
Abstract excerpt
RATIONALE: Recently, a new asthma susceptibility gene, GPRA (G-protein-related receptor for asthma), has been identified by positional cloning. Initial association studies in a Finnish and Canadian population suggested an association with asthma and elevated serum IgE levels. OBJECTIVE: In a large, nested case-control study, associations between GPRA polymorphisms, asthma, and serum IgE levels were analyzed....
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