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Article

Haplotypes of G protein-coupled receptor 154 are associated with childhood allergy and asthma.

American journal of respiratory and critical care medicine - 15 May 2005

Melén Erik, Bruce Sara, Doekes Gert, Kabesch Michael, Laitinen Tarja, Lauener Roger, Lindgren Cecilia M, Riedler Josef, Scheynius Annika, van Hage-Hamsten Marianne, Kere Juha, Pershagen Göran, Wickman Magnus, Nyberg Fredrik

Abstract excerpt

RATIONALE: Allergic diseases are influenced by both genes and environment. A 70-kb haplotype block in the G protein-coupled receptor for asthma susceptibility gene (GPR154; alias GPRA) on chromosome 7p was recently identified to influence susceptibility to asthma and elevated total serum IgE levels in adults. OBJECTIVES: To assess the impact of GPR154 on childhood allergic disease, including allergic...

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Source

Identifiers

PMID: 15710598
DOI: 10.1164/rccm.200410-1317OC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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