Article
Deregulated minichromosomal maintenance protein MCM7 contributes to oncogene driven tumorigenesis.
Oncogene - 6 Jul 2006
Honeycutt K A, Chen Z, Koster M I, Miers M, Nuchtern J, Hicks J, Roop D R, Shohet J M
Abstract excerpt
Minichromosomal maintenance protein 7 (MCM7) is an essential component of the replication helicase complex (MCM2-7) required for DNA replication. Although this function is highly conserved among eukaryotes, additional functions for the MCM molecules continue to be described. Minichromosomal maintenance protein 7 is a marker for proliferation and is upregulated in a variety of tumors including neuroblastoma,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
