Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of biomarkers that distinguish human papillomavirus (HPV)-positive versus HPV-negative head and neck cancers in a mouse model

7 Sept 2006

Abstract excerpt

Head and neck squamous cell carcinoma (HNSCC) is a leading cause of cancer mortality worldwide. Recent reports have associated a subset of HNSCC with high-risk human papillomaviruses (HPVs), particularly HPV16, the same subset of HPVs responsible for the majority of cervical and anogenital cancers. In this study we describe a mouse model for HPV-associated HNSCC that employs mice transgenic for the HPV16...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Head and Neck Cancer Studies
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16959885
DOI: 10.1073/pnas.0606698103

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of biomarkers that distinguish human papillomavirus (HPV)-positive versus HPV-negative head and neck cancers in a mouse modelPMID 16959885Read ↗

Human papillomavirus type 16 E6 and E7 oncoproteins act synergistically to cause head and neck cancer in miceSemantic proximity Read ↗

Role of Rb-dependent and Rb-independent functions of papillomavirus E7 oncogene in head and neck cancer.Semantic proximity Read ↗

Squamous epithelial hyperplasia and carcinoma in mice transgenic for the human papillomavirus type 16 E7 oncogeneSemantic proximity Read ↗

MmuPV1 E7 promotes phenotypes associated with "high-risk" HPV infection in mouse keratinocytes.Semantic proximity Read ↗

Molecular Mechanisms of MmuPV1 E6 and E7 and Implications for Human DiseaseSemantic proximity Read ↗

A mouse model for human anal cancer.Semantic proximity Read ↗

HPV-positive murine oral squamous cell carcinoma: development and characterization of a new mouse tumor model for immunological studiesSemantic proximity Read ↗

Tissue Context Shapes Distinct Premalignant Outcomes in an HPV16 E6/E7-Mutant Pik3ca Transgenic Mouse Model.Semantic proximity Read ↗

Deficiencies in the Fanconi anemia DNA damage response pathway increase sensitivity to HPV-associated head and neck cancer.Semantic proximity Read ↗

Genetically engineered mouse models of head and neck cancersSemantic proximity Read ↗

The Mus musculus papillomavirus type 1 E7 protein binds to the retinoblastoma tumor suppressor - implications for viral pathogenesisSemantic proximity Read ↗

High Incidence of HPV-Associated Head and Neck Cancers in FA Deficient Mice Is Associated with E7’s Induction of DNA Damage through Its Inactivation of Pocket ProteinsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.