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Article

In vitro suppression of CD8+ T cell function by Friend virus-induced regulatory T cells.

Journal of immunology (Baltimore, Md. : 1950) - 15 Mar 2006

Robertson Shelly J, Messer Ronald J, Carmody Aaron B, Hasenkrug Kim J

Abstract excerpt

Regulatory T cell (Treg)-mediated suppression of CD8+ T cells has been implicated in the establishment and maintenance of chronic viral infections, but little is known about the mechanism of suppression. In this study an in vitro assay was developed to investigate the suppression of CD8+ T cells by Friend retrovirus (FV)-induced Tregs. CD4+CD25+ T cells isolated from mice chronically infected with the FV...

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Source

Identifiers

PMID: 16517701
DOI: 10.4049/jimmunol.176.6.3342

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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