Article
Mouse cytomegalovirus infection overrules T regulatory cell suppression on natural killer cells.
Virology journal - 9 Aug 2014
Lindenberg Marc, Solmaz Gulhas, Puttur Franz, Sparwasser Tim
Abstract excerpt
BACKGROUND: Cytomegalovirus establishes lifelong persistency in the host and leads to life threatening situations in immunocompromised patients. FoxP3+ T regulatory cells (Tregs) critically control and suppress innate and adaptive immune responses. However, their specific role during MCMV infection, especially pertaining to their interaction with NK cells, remains incompletely defined. METHODS: To understand the...
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