Article
IL-2-independent and TNF-α-dependent expansion of Vβ5+ natural regulatory T cells during retrovirus infection.
Journal of immunology (Baltimore, Md. : 1950) - 1 Jun 2013
Myers Lara, Joedicke Jara J, Carmody Aaron B, Messer Ronald J, Kassiotis George, Dudley Jaquelin P, Dittmer Ulf, Hasenkrug Kim J
Abstract excerpt
Friend virus infection of mice induces the expansion and activation of regulatory T cells (Tregs) that dampen acute immune responses and promote the establishment and maintenance of chronic infection. Adoptive transfer experiments and the expression of neuropilin-1 indicate that these cells are p...
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