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Article

T cells with a CD4+CD25+ regulatory phenotype suppress in vitro proliferation of virus-specific CD8+ T cells during chronic hepatitis C virus infection.

Journal of virology - 1 Jun 2005

Boettler Tobias, Spangenberg Hans Christian, Neumann-Haefelin Christoph, Panther Elisabeth, Urbani Simonetta, Ferrari Carlo, Blum Hubert E, von Weizsäcker Fritz, Thimme Robert

Abstract excerpt

Chronic hepatitis C virus (HCV) infection is associated with impaired proliferative, cytokine, and cytotoxic effector functions of HCV-specific CD8(+) T cells that probably contribute significantly to viral persistence. Here, we investigated the potential role of T cells with a CD4(+)CD25(+) regu...

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Share to CD4 Antigens
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15919940
DOI: 10.1128/JVI.79.12.7860-7867.2005
PMCID: PMC1143651

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-15919940-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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