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Article

Regulatory T cells prevent control of experimental African trypanosomiasis.

Journal of immunology (Baltimore, Md. : 1950) - 15 Feb 2008

Wei Guojian, Tabel Henry

Abstract excerpt

African trypanosomes are single-cell, extra-cellular blood parasites causing profound immunosuppression. Susceptible BALB/c mice infected s.c. into a footpad with 10(4) Trypanosoma congolense die with fulminating parasitemia within 10 days. We injected BALB/c mice 2 days before such an infection with different doses of a depleting mAb specific for CD25, a surface marker of regulatory T cells (Tregs). Pretreatment...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-2 Receptor alpha Subunit

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Source

Identifiers

PMID: 18250461
DOI: 10.4049/jimmunol.180.4.2514

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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