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Article

Microsatellite instability in mitochondrial genome of common female cancers.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Jan 2000

Wang Y, Liu V W S, Tsang P C K, Chiu P M, Cheung A N Y, Khoo U S, Nagley P, Ngan H Y S

Abstract excerpt

To investigate the occurrence of mitochondrial genome instability in primary cervical, endometrial, ovarian, and breast carcinomas, we analyzed 12 microsatellite regions in mitochondrial DNA (mtDNA) of tumor tissues and their matched normal controls. Four of the 12 microsatellite markers starting at nucleotide position (np) 303, 514, 956, and 16184, respectively, exhibited instability as indicated by the change...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16515601
DOI: 10.1111/j.1525-1438.2006.00412.x

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