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Article

Mitochondrial genome instability in human cancers.

Mutation research - 1 Mar 2001

Bianchi N O, Bianchi M S, Richard S M

Abstract excerpt

Malfunction of mismatch repair (MMR) genes produces nuclear genome instability (NGI) and plays an important role in the origin of some hereditary and sporadic human cancers. The appearance of non-inherited microsatellite alleles in tumor cells (microsatellite instability, MSI) is one of the expressions of NGI. We present here data showing mitochondrial genome instability (mtGI) in most of the human cancers...

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Identifiers

PMID: 11223402
DOI: 10.1016/s1383-5742(00)00063-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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