Article
Mitochondrial genome instability in human cancers.
Mutation research - 1 Mar 2001
Bianchi N O, Bianchi M S, Richard S M
Abstract excerpt
Malfunction of mismatch repair (MMR) genes produces nuclear genome instability (NGI) and plays an important role in the origin of some hereditary and sporadic human cancers. The appearance of non-inherited microsatellite alleles in tumor cells (microsatellite instability, MSI) is one of the expre...
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