The effect of assortative mating upon genetic association studies: spurious associations and population substructure in the absence of admixture.

Abstract excerpt

Spurious associations due to confounding factors are an often cited and intensely debated concern for genetic association studies. Great attention has been focused upon the specific threat of confounding due to population stratification. This emphasis has spurred the development of many statistical genetic methods to detect and correct for the potentially confounding effects of admixture. Unfortunately, this...

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