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Article

Control of confounding of genetic associations in stratified populations.

American journal of human genetics - 1 Jun 2003

Hoggart Clive J, Parra Eteban J, Shriver Mark D, Bonilla Carolina, Kittles Rick A, Clayton David G, McKeigue Paul M

Abstract excerpt

To control for hidden population stratification in genetic-association studies, statistical methods that use marker genotype data to infer population structure have been proposed as a possible alternative to family-based designs. In principle, it is possible to infer population structure from associations between marker loci and from associations of markers with the trait, even when no information about the...

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Identifiers

PMID: 12817591
DOI: 10.1086/375613
PMCID: PMC1180309

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