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Article

Role of IL-12B promoter polymorphism in Adamantiades-Behcet's disease susceptibility: An involvement of Th1 immunoreactivity against Streptococcus Sanguinis antigen.

The Journal of investigative dermatology - 1 Jul 2006

Yanagihori Hirokatsu, Oyama Noritaka, Nakamura Koichiro, Mizuki Nobuhisa, Oguma Keiji, Kaneko Fumio

Abstract excerpt

Adamantiades-Behcet's disease (ABD) is a chronic inflammatory multisystem disorder. Although the precise etiology is unclear, high prevalence of human leukocyte antigen (HLA)-B51 predisposition and predominantly involved T-helper type 1 cells (Th1)-type proinflammatory cytokines and extrinsic Streptococcal infection suggest a substantial association with an immunogenetic basis and strengthens the hypothesis that...

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Source

Identifiers

PMID: 16514412
DOI: 10.1038/sj.jid.5700203

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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