Article
Pathological implications of Th1/Th2 cytokine genetic variants in Behçet's disease: Data from a pilot study in a Sicilian population.
Biochemical genetics - 1 Dec 2013
Vaccarino L, Triolo G, Accardo-Palombo A, Scola L, Palmeri M, Bova M, Candore G, Lio D, Balistreri C R
Abstract excerpt
Cytokines act as pleiotropic polypeptides able to regulate inflammatory/immune responses and to provide important signals in physiological and pathological processes. Several cytokines (Th1, Th2, and Th17) seem to be involved in the pathophysiology of Behçet's disease, a chronic immune-mediated disease characterized by oral and genital lesions and ocular inflammation. Its individual susceptibility seems to be...
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