Article
A new method for fast haptoglobin phenotyping and hemoglobin binding capacity calculation based on capillary zone electrophoresis.
Clinical chemistry and laboratory medicine - 1 Aug 2000
Wuyts B, Delanghe J R, Kasvosve I, Langlois M R, De Buyzere M L, Janssens J
Abstract excerpt
A capillary zone electrophoresis method was developed for haptoglobin (Hp) phenotyping in hemoglobin (Hb) supplemented serum. The method allows a complete resolution of the major haptoglobin phenotypes Hp 1-1, Hp 2-1, and Hp 2-2 based on the difference in charge-to-mass ratio of their Hb-Hp complexes. Identification of these phenotypes was achieved by their significant differences in migration times and their...
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