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<i>CYP2B6</i>*<i>6</i>single nucleotide polymorphism among patients with uncomplicated malaria in Adjumani district, Uganda: implications on efficacy of artemether-lumefantrine

2025-06-14

Abstract excerpt

CYP2B6, one of the most polymorphic enzymes, plays a major role in the metabolism of artemisinin and its derivatives. Variation in the frequency of the most common yet functionally deficient CYP2B6*6 allele may impact artemisinin exposure, potentially contributing to differences in treatment outcomes. This study assessed the prevalence of the CYP2B6*6 genotype among patients with uncomplicated malaria treated with...

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Literature Corpus work
decc7d7c-0e76-5a9c-a054-5d605a141d76
DOI
10.1101/2025.06.13.25329585
Open publication

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<i>CYP2B6</i>*<i>6</i>single nucleotide polymorphism among patients with uncomplicated malaria in Adjumani district, Uganda: implications on efficacy of artemether-lumefantrineDOI 10.1101/2025.06.13.25329585
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