Article
Significance of Hereditary Hemochromatosis Gene (HFE) Mutations in Chronic Hepatitis C and Hepatocellular Carcinoma Patients in Egypt: A Pilot Study.
Asian Pacific journal of cancer prevention : APJCP - 1 Sept 2021
Dawood Reham M, Abd El Meguid Mai, Elrobe Walied, Salum Ghada M, Zayed Naglaa, Mousa Sherief, Medhat Eman
Abstract excerpt
BACKGROUND: Hereditary hemochromatosis is a genetic disease defined by enhanced overloading of iron and associated with Chronic Hepatitis C (CHC). This study aims to evaluate the correlation of the HFE gene mutations on Egyptian CHC with liver disease progression and the risk of HCC development. METHODS: The HFE mutations (C282Y and H63D) were genotyped on 100 CHC patients and 50 healthy individuals by a...
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