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Article

Association of the Leukocyte Immunoglobulin-like Receptor A3 Gene With Neutrophil Activation and Disease Susceptibility in Adult-Onset Still's Disease.

Arthritis & rheumatology (Hoboken, N.J.) - 1 Jun 2021

Wang Mengyan, Liu Mengru, Jia Jinchao, Shi Hui, Teng Jialin, Liu Honglei, Sun Yue, Cheng Xiaobing, Ye Junna, Su Yutong, Chi Huihui, Liu Tingting, Wang Zhihong, Wan Liyan, Meng Jianfen, Ma Yuning, Yang Chengde, Hu Qiongyi

Abstract excerpt

OBJECTIVE: Adult-onset Still's disease (AOSD) is a severe autoinflammatory disease. Neutrophil activation with enhanced neutrophil extracellular trap (NET) formation is involved in the pathogenesis of AOSD. Functional leukocyte immunoglobulin-like receptor A3 (LIR-A3; gene name LILRA3) has been reported to be associated with many autoimmune diseases. We aimed to investigate the association of LILRA3 with disease...

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Identifiers

PMID: 33381895
DOI: 10.1002/art.41635
PMCID: PMC8252061

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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